Rejuran Program
Renew and Restore Your Skin
Rejuran Program
Renew and Restore Your Skin from Within
for Smoother, Healthier-Looking Skin
Skin quality is not only about how the skin looks on the surface. It is an important foundation that reflects the overall health and strength of the skin’s underlying structure. When the skin structure becomes weakened or compromised, various skin concerns may gradually develop like a domino effect, including dullness, enlarged pores, uneven skin texture, and slower skin recovery.
On the other hand, when the skin is properly supported and restored from within, it can gradually become smoother, plumper, and healthier-looking, with improved overall skin quality and a more natural appearance.
One treatment designed to support skin repair and rejuvenation at a deeper level is the Rejuran treatment. Rejuran is a popular skin rejuvenation treatment that focuses on improving overall skin quality, skin texture, and skin regeneration, helping strengthen and restore the skin from within.
In this article, Seven Days Clinic will introduce you to the Rejuran treatment, including what Rejuran is, how it works, its potential skin benefits, and who may be suitable for the treatment, helping you better understand this approach to skin rejuvenation and skin repair.
What Is Rejuran?
Rejuran is an injectable skin rejuvenation treatment widely recognized in aesthetic medicine and used in many countries worldwide. It is designed to support skin regeneration and improve overall skin quality from within while maintaining natural-looking results.
The key active ingredient in Rejuran is Polynucleotide (PN), a highly purified substance derived from fragments of salmon DNA. Polynucleotides are biocompatible with the human body and are used to support the skin’s natural repair and regeneration processes.
Rather than focusing primarily on adding facial volume, Rejuran PN treatment is designed to improve the overall condition of the skin. It may help support healthier-looking skin, improve uneven skin texture, enhance skin elasticity, and promote a smoother and more refined appearance.
After the Rejuran treatment, small raised bumps may temporarily appear at the injection sites. This is a common post-treatment reaction and typically subsides within approximately 1–3 days. Most patients can resume their normal daily activities, and makeup can generally be applied the following day, depending on the physician’s assessment and individual skin condition.
What Is PN – Polynucleotide?
Polynucleotide (PN) is a heat-stable, highly biocompatible substance that is generally well tolerated by the human body. In aesthetic medicine, PN is widely used in skin rejuvenation treatments to support the skin’s natural repair and regeneration processes.
Key benefits of Polynucleotide (PN) include:
- upports the skin’s natural self-regeneration process and helps maintain a balanced skin environment.
- Helps improve skin elasticity by supporting the condition of both the epidermis and dermis.
- Supports the natural repair of skin affected by environmental stressors and helps restore the skin structure from within.
- Helps improve overall skin quality, skin texture, and skin resilience, contributing to healthier-looking skin over time.
Because of these properties, PN has become an important ingredient in Rejuran skin rejuvenation treatments, particularly for those looking to improve overall skin quality rather than simply add facial volume.
How Does Rejuran Work?
The key active ingredient in Rejuran treatment is Polynucleotide (PN), which is derived from highly purified fragments of salmon DNA. The material undergoes a specialized purification and manufacturing process designed to minimize antigenic components and enhance its biocompatibility with human skin.
When injected into the skin, PN acts as a supportive component for skin repair and regeneration, helping create a favorable environment for the skin’s natural recovery processes.
The mechanism of Rejuran PN treatment involves supporting several important skin functions, including:
- Supporting the activity of fibroblast cells, which play an important role in the production of collagen and elastin.
- Promoting the natural repair and regeneration of damaged or weakened skin tissue.
- Supporting skin recovery following irritation or inflammation.
- Helping improve the overall skin environment and supporting stronger, healthier-looking skin over time.
Some clinical studies have also investigated the potential role of Polynucleotide injections in supporting skin density, tissue regeneration, and continued skin recovery. However, individual results may vary depending on factors such as baseline skin condition, age, lifestyle, treatment protocol, and aftercare.
Following a course of Rejuran skin rejuvenation treatments, the skin may gradually appear healthier, smoother, and more balanced. Improvements may also be seen in uneven skin texture, redness, post-inflammatory marks, skin elasticity, and overall skin quality, particularly in individuals with weakened, sensitive, or easily irritated skin.
Key Benefits of Rejuran Treatment
- Deep Skin Rejuvenation (Excellent Recovery Effect)
Rejuran treatment supports the skin’s natural self-regeneration and repair processes, helping improve multiple skin concerns such as fine lines, acne scars, enlarged pores, redness, uneven skin tone, and dullness.
- Improves Skin Elasticity and Fine Wrinkles
Rejuran helps support collagen production and the restoration of the Extracellular Matrix (ECM) within the skin. This may help skin affected by aging and environmental stressors appear firmer and more elastic while reducing the appearance of fine lines and wrinkles.
- Improves Skin Tone and Texture
Rejuran PN helps improve overall skin tone and texture, promoting a brighter, smoother, and more refined appearance while reducing visible unevenness in the skin.
- High Biocompatibility and Established Safety Profile
Rejuran contains highly purified Polynucleotide (PN) derived from DNA fragments. PN has high biocompatibility with the human body and has been developed for use in regenerative and aesthetic applications. As with any injectable treatment, temporary reactions such as redness, swelling, bruising, or small raised bumps at the injection sites may occur.
- Promotes Naturally Youthful-Looking Skin (Natural Skin Beauty Effect)
Rather than simply adding volume, Rejuran skin rejuvenation treatment focuses on improving overall skin quality from within. It helps support skin hydration, elasticity, texture, and resilience, resulting in healthier, smoother, plumper, and naturally youthful-looking skin.
10 Specific Benefits of Rejuran Treatment
- Helps improve skin firmness for a firmer, more refreshed appearance.
- Helps enhance skin elasticity and resilience.
- Helps improve uneven skin texture and skin tone.
- Helps reduce the appearance of fine lines and wrinkles.
- Supports the recovery and function of the skin barrier.
- Helps maintain a better balance between skin hydration and oil levels.
- Helps minimize the appearance of enlarged pores.
- Helps support balanced sebum production for healthier-looking skin.
- Supports healthier skin renewal, helping improve rough or uneven skin texture.
- Rejuran PN has been clinically studied for its biocompatibility, safety, and potential role in skin repair and rejuvenation.
Rejuran Treatments Available at Seven Days Clinic
The Rejuran treatments available at Seven Days Clinic contain Polynucleotide (PN), a highly purified substance derived from salmon DNA. PN is processed to achieve high biocompatibility with the human body and is used to support skin repair, regeneration, and overall skin rejuvenation at a deeper level.
At Seven Days Clinic, we primarily offer two Rejuran formulations: Rejuran Healer and Rejuran HB Plus. Each formulation has distinct properties and is designed to address different skin concerns and treatment goals.
Rejuran Healer – For Deep Skin Repair and Skin Quality Improvement
Rejuran Healer is a concentrated Polynucleotide (PN) skin rejuvenation treatment designed to focus on improving overall skin quality and supporting the skin’s natural regeneration process.
It is particularly suitable for those looking to address concerns such as weakened or compromised skin, uneven skin texture, enlarged pores, and post-acne marks while supporting healthier-looking skin over time.
Who Is Rejuran Healer Suitable For?
- Those with weakened or compromised skin and concerns about skin barrier function
- Those with enlarged pores or uneven skin texture
- Those with post-acne marks or uneven-looking skin
- Those who want to improve overall skin quality and skin resilience over time
Rejuran HB Plus – Hydro Booster for Skin Repair and Hydration (
Rejuran HB Plus (Hydro Booster) combines Polynucleotide (PN) with Hyaluronic Acid (HA) to support skin rejuvenation while providing additional hydration. This combination is designed for those who want to improve overall skin quality while addressing dryness and dehydration.
By combining the regenerative properties of PN with the hydrating benefits of Hyaluronic Acid, Rejuran HB Plus helps the skin appear more hydrated, plump, smooth, and naturally radiant.
Who Is Rejuran HB Plus Suitable For?
- Those with dry, dehydrated, or unbalanced skin
- Those who want skin rejuvenation combined with enhanced hydration
- Those with dull or tired-looking skin that lacks natural radiance
- Those who want their skin to appear plumper, more hydrated, radiant, and healthy-looking
Rejuran Healer vs. Rejuran HB Plus Comparison
In general, Rejuran Healer is more focused on skin regeneration and overall skin quality improvement, while Rejuran HB Plus combines Polynucleotide (PN) and Hyaluronic Acid (HA) for those who want both skin rejuvenation and enhanced hydration.
Who Is Not Suitable for Rejuran Treatment?
Rejuran treatment may not be suitable for everyone. A consultation with a qualified physician is recommended before treatment, particularly for individuals with certain medical conditions or specific skin concerns.
- Those with an active skin infection or inflammation in the treatment area
- Those with a known allergy or hypersensitivity to ingredients in Polynucleotide (PN) products or salmon-derived components
- Those who are pregnant or breastfeeding should consult a physician before considering treatment
- Those with certain medical conditions affecting the immune system, or those taking medications that may affect blood clotting
- Those with unrealistic expectations, such as expecting an immediate and significant change in facial structure, as Rejuran primarily focuses on skin quality and skin rejuvenation rather than facial volumization or contouring
A physician should assess the individual’s skin condition, medical history, and treatment goals to determine whether Rejuran PN treatment is appropriate.
What Areas Can Rejuran Be Injected Into?
Rejuran injections can be used in several areas where improvement in skin quality, texture, hydration, and regeneration is desired. The appropriate treatment areas and injection technique should be determined by a physician based on individual skin concerns.
- Full Face – Helps support overall skin rejuvenation, promoting smoother, healthier-looking, and more resilient skin.
- Under-Eye Area – Helps improve the appearance of dullness and supports the quality of the delicate skin around the eyes.
- Cheeks – Helps improve uneven skin texture and reduce the appearance of enlarged pores.
- Forehead – Helps promote smoother, more even-looking skin and improve overall skin texture.
- Perioral Area – Helps improve dryness and reduce the appearance of fine lines around the mouth.
- Acne Scar / Scar Areas – Supports the skin’s natural repair and regeneration processes, helping improve the appearance of uneven skin texture and acne scars over time.
Rejuran Treatment Procedure
The Rejuran treatment procedure is performed by a physician and tailored to each individual’s skin condition, concerns, and treatment goals.
- The physician assesses the patient’s skin condition and develops an individualized treatment plan.
- The skin is thoroughly cleansed and the treatment area is prepared.
- A topical anesthetic may be applied to help minimize discomfort during the procedure, depending on the treatment area and individual needs.
- The physician carefully administers Rejuran injections into the appropriate layer of the skin using a suitable injection technique.
- After the procedure, initial skin care is provided, along with personalized Rejuran aftercare instructions to support skin recovery.
How to Prepare Before Rejuran Treatment
Proper preparation before a Rejuran PN treatment can help minimize temporary side effects such as bruising and support a smoother recovery process.
- Certain medications or supplements that may affect blood clotting, such as aspirin or specific supplements, may need to be avoided approximately 3–7 days before treatment. However, prescribed medications should never be discontinued without consulting your physician.
- Avoid alcohol for at least 24–48 hours before the treatment.
- Inform your physician if you have active acne, inflammation, rashes, infections, or other skin conditions in the treatment area.
- Get adequate rest and maintain good hydration before your appointment.
Rejuran Aftercare: What to Do After Treatment
Following proper Rejuran aftercare can help support the skin’s recovery and minimize unnecessary irritation after the injections.
- Avoid pressing, rubbing, or massaging the treated areas.
- Avoid applying makeup for approximately 24 hours, or until the skin has settled, according to your physician’s recommendations.
- Avoid excessive heat exposure, including saunas, hot baths, and intense sun exposure, for approximately 1–3 days after treatment.
- Use gentle skincare products and temporarily avoid potentially irritating active ingredients as recommended by your physician.
- Apply broad-spectrum sunscreen regularly to protect the skin during the recovery period.
Small raised bumps, mild redness, swelling, or bruising may temporarily occur at the injection sites. These reactions generally improve gradually after treatment. If unusual or persistent symptoms occur, patients should contact their physician for further evaluation.
How Many Rejuran Treatments Are Recommended?
In general, Rejuran treatment is performed as a series of sessions to support progressive skin repair, regeneration, and skin quality improvement. Rather than creating an immediate volumizing effect, Rejuran works gradually as the skin undergoes its natural renewal process.
The recommended number of sessions and treatment intervals may vary depending on individual skin condition, age, concerns, and the physician’s treatment plan. Changes may gradually become noticeable throughout the treatment course.
After the 1st Treatment – Approximately 3–5 Days (
- Skin may begin to feel smoother and softer.
- Overall skin balance may begin to improve.
- Skin may appear more hydrated and refreshed.
After the 2nd Treatment – Approximately 2–4 Weeks
- Skin elasticity may gradually improve.
- Fine lines may appear less noticeable.
- The appearance of enlarged pores may be reduced.
- Overall skin texture may appear smoother and more even.
After the 3rd Treatment – Approximately 4–6 Weeks
- Skin may appear naturally firmer and more resilient.
- The dermal structure is supported through the skin’s ongoing regenerative processes.
- Overall skin quality, texture, and elasticity may become more noticeable.
After the 4th Treatment – Approximately 6–8 Weeks
- The cumulative effects of skin rejuvenation may become more noticeable.
- Skin may appear smoother, healthier, and naturally more youthful.
- Improvements may be seen across multiple aspects of skin quality, including hydration, texture, elasticity, firmness, and overall skin appearance.
Individual results and the timeline of improvement can vary. A physician should assess the skin and determine the appropriate Rejuran treatment frequency and number of sessions for each patient.
How Is Rejuran Different from Other Skin Boosters?
Rejuran treatment differs from conventional skin booster treatments in both its key active ingredient and its primary approach to skin rejuvenation. While many skin boosters mainly focus on hydration and creating a plumper, dewy appearance, Rejuran is designed to support skin repair and regeneration at a deeper level, with an emphasis on improving overall skin quality and skin structure.
Key Ingredients and Mechanism of Action
Rejuran
Rejuran contains Polynucleotide (PN), highly purified DNA fragments that support the skin’s natural repair and regeneration processes. PN helps create a favorable environment for skin recovery and supports fibroblast activity, which plays an important role in the production of collagen and elastin.
Skin Booster
ทั่วไป ส่วนใหญ่ใช้ Hyaluronic Acid (HA) เป็นหลักเน้นการเพิ่มความชุ่มชื้น เติมน้ำให้ผิว และช่วยให้ผิวดูอิ่มฟูแบบชั่วคราว
Treatment Goals
Rejuran
Rejuran focuses on skin quality improvement and regeneration, helping support healthier and more resilient skin from within. It may be particularly beneficial for concerns such as weakened skin, enlarged pores, uneven skin texture, and other signs associated with declining skin quality.
Skin Booster
เน้น “เพิ่มความชุ่มชื้นและความโกลว์” เหมาะสำหรับผิวแห้งหรือผิวที่ต้องการความฉ่ำวาวเป็นหลัก
Results
Rejuran
- Supports healthier and more resilient skin over time
- Helps improve uneven skin texture
- Helps reduce the appearance of enlarged pores
- Supports better skin balance and natural recovery
- Helps improve overall skin quality and elasticity
Skin Booster
- Provide enhanced skin hydration
- Help the skin appear plumper and more refreshed
- Promote a dewy, radiant, and glowing complexion
- Effects on deeper skin regeneration may vary depending on the ingredients and formulation used
Longevity and Treatment Approach
Rejuran
Rejuran focuses on progressive skin rejuvenation and regeneration. Rather than simply providing hydration, Polynucleotide (PN) supports the skin’s natural repair processes, meaning improvements in skin quality may gradually become more noticeable over a course of treatments.
Skin Booster
Many skin boosters provide hydration-focused benefits that may be noticeable relatively quickly. Maintenance treatments are generally recommended to help sustain hydration and the desired skin appearance. However, results and longevity vary depending on the type of skin booster, formulation, and individual skin condition.
Rejuran is an advanced skin rejuvenation treatment designed to support deeper skin repair and improve overall skin quality through Polynucleotide (PN). By supporting the skin’s natural regeneration processes, Rejuran can help the skin gradually appear smoother, stronger, more balanced, and healthier-looking.
It may be suitable for individuals looking to address a range of skin concerns, including weakened skin, enlarged pores, post-acne marks, uneven skin texture, fine lines, and declining skin quality. Unlike treatments that primarily focus on providing hydration, Rejuran takes a regenerative approach to supporting healthier-looking skin from within.
For those looking for more than just a temporary hydration boost and who want to focus on skin repair, regeneration, and long-term skin quality improvement, Rejuran may be an appropriate treatment option.
You can book a consultation with a physician at Seven Days Clinic to assess your skin condition and determine whether Rejuran treatment is suitable for your individual skin concerns and goals.
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