Vitaran PN Treatment is an advanced skin rejuvenation treatment formulated with 2% Polynucleotide (PN) (20 mg/ml), extracted from highly purified Sea Trout DNA. The PN molecules are carefully controlled within a molecular weight range of approximately 390–1,300 kDa (Kilodaltons).

This optimized molecular size allows Polynucleotide to remain within the skin for an appropriate period, where it acts as a three-dimensional (3D) scaffold that supports tissue repair and promotes the skin's natural regeneration process. Once injected into the skin, Vitaran PN helps to:


• Stimulate fibroblast activity
• Support natural collagen and elastin production
• Improve skin hydration
• Help reduce micro-inflammatory responses within the skin
• Promote the repair of damaged skin cells
• Strengthen the skin's natural protective barrier (Skin Barrier)

Rather than adding volume like dermal fillers, Vitaran focuses on restoring skin quality from within. The result is skin that appears smoother, more hydrated, firmer, and naturally healthier over time.

Vitaran PN Treatment is designed to improve overall skin quality from within using Polynucleotide (PN). It targets four common skin concerns through natural skin regeneration.

1. RED – Redness and Skin Sensitivity


Common Concerns

• Easily irritated or sensitive skin
• Persistent redness
• Inflammation caused by pollution, UV exposure, aesthetic procedures, or a weakened skin barrier



How PN Helps

Vitaran PN supports the skin's natural repair process while helping reduce micro-inflammation. It also strengthens the skin barrier, making the skin more resilient against external environmental stressors.

2. SMOOTH – Rough Skin and Enlarged Pores


Common Concerns

• Uneven skin texture
• Enlarged pores
• Loss of elasticity
• Mild acne scars

How PN Helps

Vitaran PN stimulates fibroblasts, the key cells responsible for producing collagen and elastin. This continuous regeneration process helps improve skin structure, leaving the skin smoother, firmer, and more refined.

3. DULL – Dull and Dehydrated Skin


Common Concerns

• Dry, dehydrated skin
• Dull complexion
• Tired-looking skin lacking radiance


How PN Helps

Vitaran PN improves the skin's ability to retain moisture while supporting a healthier cellular environment. Well-hydrated skin appears brighter, plumper, and more radiant.

4. DARK – Uneven Skin Tone and Post-Acne Marks


Common Concerns

• Uneven skin tone
• Post-inflammatory hyperpigmentation (PIH)
• Acne marks
• Dark under-eye appearance



How PN Helps

As the skin repairs itself and cellular function improves, overall skin quality becomes healthier. This contributes to a more even-looking complexion and naturally brighter skin over time.

1. Long Retention PN

Vitaran contains Polynucleotide (PN) with a carefully controlled molecular weight of 390–1,300 kDa. These molecules function as a 3D scaffold, allowing PN to remain in the skin for an appropriate duration and continuously support the skin's natural repair and regeneration process.


2. Low Pain Formula

Vitaran features Pain Control Technology, with an optimized viscosity designed to improve injection comfort. This formulation helps minimize discomfort during treatment compared with some other Polynucleotide products.


3. Ultra Pure Extract

The Polynucleotide used in Vitaran is extracted from Sea Trout DNA sourced from closed-system aquaculture and undergoes a highly purified manufacturing process. This helps reduce impurities while supporting product quality and safety.


4. Regenerative Skin Repair

Beyond improving hydration, Vitaran supports the skin's natural repair process by promoting fibroblast activity, collagen production, and healthier skin regeneration from within.


5. Natural-Looking Results

Unlike dermal fillers that primarily restore facial volume, Vitaran focuses on improving overall skin quality. The result is skin that looks healthier, smoother, firmer, and naturally radiant without noticeably altering facial contours.

Vitaran PN Treatment can be used to improve skin quality in multiple areas of the body. Your doctor will assess your skin condition and create a personalized treatment plan based on your individual concerns. Common treatment areas include:



• Fine lines and wrinkles
• Under-eye area
• Stretch marks
• Facial skin concerns such as enlarged pores, uneven texture, and loss of firmness
• The backs of the hands for skin rejuvenation

Vitaran PN Treatment may be suitable for individuals who want to improve overall skin quality and are experiencing concerns such as:



• Dry or dehydrated skin
• Dull, tired-looking skin
• Uneven skin tone
• Post-acne marks and hyperpigmentation
• Redness or sensitive skin
• Enlarged pores
• Rough or uneven skin texture
• Loss of skin elasticity
• Fine lines and early signs of aging

Although Vitaran PN Treatment is suitable for many skin types, some individuals should consult a qualified physician before undergoing treatment, particularly those who:

• Have a known allergy to any ingredient in the product
• Have a history of allergies to fish or seafood
• Have an active skin infection, inflammation, or abscess in the treatment area
• Have certain skin conditions affecting the intended injection site
• Are pregnant or breastfeeding
• Have underlying medical conditions or are taking medications that may affect treatment suitability



A medical consultation is recommended to determine whether the treatment is appropriate for your individual condition.

Both Vitaran PN Treatment and Rejuran are skin rejuvenation treatments based on Polynucleotide (PN) technology. They are designed to improve skin quality from within by supporting the skin's natural repair process, stimulating collagen production, and promoting healthier, more resilient skin.

Although both treatments share a similar mechanism of action, they differ in several aspects, including:

• Source of the Polynucleotide (PN)
• Manufacturing and purification processes
• Purity and formulation
• Injection experience and treatment comfort

Understanding these differences can help you and your physician choose the treatment that best matches your skin concerns and aesthetic goals.

To help ensure a smooth treatment experience and minimize the risk of bruising or other side effects, it is recommended to follow these preparation guidelines before undergoing Vitaran PN Treatment:

• Schedule a consultation with a qualified physician for a skin assessment and personalized treatment plan.
• Inform your doctor about any allergies, especially allergies to medications, fish, or seafood.
• Tell your physician if you are pregnant, breastfeeding, have underlying medical conditions, or are taking prescription medications.
• Follow your doctor's advice regarding medications, vitamins, or dietary supplements that may increase the risk of bruising.
• Avoid alcohol for at least 24 hours before treatment.
• Stay well hydrated and get sufficient rest before your appointment.
• Avoid skin treatments that may irritate the skin prior to your procedure.
• Arrive with clean skin and avoid wearing heavy makeup on the day of treatment.



Preparation may vary depending on your individual health condition. Always follow your physician's instructions before treatment.

Proper aftercare helps support skin recovery and optimize treatment results.After Vitaran PN Treatment, it is recommended to:

• Avoid touching, rubbing, massaging, or applying pressure to the treated area for 24 hours.
• Avoid wearing makeup for the first 24 hours.
• Refrain from strenuous exercise on the day of treatment.
• Avoid saunas, steam rooms, hot baths, and excessive heat exposure for approximately 48 hours.
• Protect your skin from excessive sun exposure and apply sunscreen daily.
• Drink plenty of water to help maintain skin hydration.
• Use gentle skincare products and avoid potentially irritating ingredients during the recovery period.
• Mild redness, small injection marks, or slight swelling at the injection sites are common and usually resolve within a few days.
• Follow all post-treatment instructions provided by your physician and attend any recommended follow-up appointments.
• Contact your clinic promptly if you experience severe or persistent swelling, redness, pain, or any unusual symptoms.

At Seven Days Clinic, every treatment is tailored to your individual skin condition and aesthetic goals. Our approach includes:

Comprehensive skin assessment and treatment planning by experienced physicians

Authentic, high-quality products that are fully traceable

Personalized injection techniques based on your unique skin concerns

Complete care before, during, and after your treatment

Strict hygiene and safety standards throughout every procedure

Customized treatment plans designed specifically for each patient

A commitment to helping you achieve healthier, smoother, and naturally youthful-looking skin

Vitaran PN Treatment is an advanced Polynucleotide (PN) skin rejuvenation treatment designed to improve skin quality from within. By supporting the skin's natural repair process, enhancing hydration, stimulating collagen production, and strengthening the skin barrier, Vitaran helps promote smoother, healthier, and more radiant-looking skin with natural-looking results.

It may be suitable for individuals experiencing dry or dehydrated skin, dull complexion, weakened skin barrier, enlarged pores, fine lines, or those seeking long-term skin quality improvement through the principles of Longevity Skin Care.

If you're interested in discovering whether Vitaran PN Treatment is right for you, we invite you to schedule a consultation with the experienced physicians at Seven Days Clinic. Our team will assess your skin condition, discuss your concerns, and create a personalized treatment plan tailored to your skin's unique needs.